Key result
Radiographic esophageal imaging improved the success rate of transseptal catheterization compared to the Ross technique (99.6% vs. 45.7%, p = 0.0001) during percutaneous balloon mitral valvuloplasty.
Why the study?
Does radiographic esophageal imaging improve the success rate of transseptal catheterization in patients undergoing percutaneous balloon mitral valvuloplasty?
RCT (n=468)
Does radiographic esophageal imaging improve the success rate of transseptal catheterization in patients undergoing percutaneous balloon mitral valvuloplasty?
Absolute Event Rate: 99.6% vs 45.7%
p-value: p=0.0001
Radiographic esophageal imaging significantly improves the success rate of transseptal catheterization during percutaneous balloon mitral valvuloplasty in patients with severe left atrial enlargement.
Supports radiographic esophageal imaging for transseptal access in PBMV; confirms marked superiority over Ross technique in RCT.
OBJECTIVE: To investigate the value of radiographic esophageal imaging in facilitating transseptal catheterization in patients undergoing percutaneous balloon mitral valvuloplasty. SUBJECTS AND METHODS: A total of 468 patients were randomized into either the study group (n = 234), in which radiographic esophageal imaging by the oral administration of a contrast media took place, or the control group (n = 234), in which the Ross technique was used. Of the 468 patients, 203 were males and 265 were females. The average ages of the study and control groups were 53 +/- 16 and 51 +/- 17 years, respectively. The patients had severe left atrial enlargement, as measured using 2-dimensional echocardiography. RESULTS: In the study group, the left atrial impression on the esophagus was clearly seen, and was used to identify the puncture site on the right atrial side for the passage of the transseptal catheter. In the control group, the left atrial silhouette was not clearly shown by fluoroscopy in 112 patients (47.5%). The success rate of transseptal catheterization in the study group was higher than in the control group (99.6 vs. 45.7%, p = 0.0001). There were no complications in the study group, but pericardial tamponade occurred in 1 patient in the control group. CONCLUSION: Radiographic esophageal imaging facilitates the identification of an optimal atrial transseptal puncture site, and improves the success rate of transseptal catheterization in patients undergoing percutaneous balloon mitral valvuloplasty.
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Wu et al. (2008) conducted an RCT in Severe left atrial enlargement requiring percutaneous balloon mitral valvuloplasty (n=468). Radiographic esophageal imaging vs. Ross technique was evaluated on Success rate of transseptal catheterization (p=0.0001). Radiographic esophageal imaging improved the success rate of transseptal catheterization compared to the Ross technique (99.6% vs. 45.7%, p = 0.0001) during percutaneous balloon mitral valvuloplasty.
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