Key result
Percutaneous balloon mitral valvuloplasty significantly improved right ventricular function, with significant changes in TAPSE (P=0.008) and Tie index (P=0.008) at 24 hours.
Why the study?
Does percutaneous balloon mitral valvuloplasty improve right ventricular function in patients with rheumatic mitral stenosis?
Observational (n=30)
No
Does percutaneous balloon mitral valvuloplasty improve right ventricular function in patients with rheumatic mitral stenosis?
p-value: p=0.008
Successful percutaneous balloon mitral valvuloplasty is associated with significant improvement in echocardiographic parameters of right ventricular systolic and diastolic function.
Supports post-PBMV RV monitoring in rheumatic MS; leaves open confirmation of clinical benefit in prospective trials.
Rheumatic cardiac disease is an immunologic phenomenon that may affect any of the heart valves and is by far the most common cause of mitral stenosis. To evaluate impact of successful percutaneous balloon mitral valvuloplasty on right ventricular function. 30 consecutive patients who underwent balloon mitral valvuloplasty for rheumatic mitral stenosis between September 2010 and July 2011 at Ain Shams University hospital were included. All patients were subjected to transthoracic echo Doppler study, tissue Doppler imaging and TEE for: (A) Assessment of severity of mitral stenosis. (B) Peak myocardial velocities during systole, early and late diastole. (C) Assessment of RV function by measurement of TAPSE and Tie index. The study revealed a significant drop in TAPSE (before and 24 h after, P 0.008; before and 3 ms after, P 0.001) respectively. There was no significant change 24 h and 3 ms after the procedure (P 0.220) .There was no significant change in IVC flow before and after 24 h (P 0.221). There was no significant drop between before and after 3 ms (P 0.062). There was no significant change between 24 h and 3 ms after the procedure (P 0.264). There was a significant drop in Tie index (before and 24 h after, P 0.008; before and 3 ms after, P 0.009) respectively but no significant drop was found 24 h and 3 ms after the procedure (P 0.373). The current study showed a significant improvement in both systolic and diastolic functions of RV as observed by different echocardiographic parameters post BMV in patients without organic TV disease.
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Morttada et al. (2014) conducted an observational in rheumatic mitral stenosis (n=30). percutaneous balloon mitral valvuloplasty vs. baseline was evaluated on right ventricular function (TAPSE and Tie index) (p=0.008). Percutaneous balloon mitral valvuloplasty significantly improved right ventricular function, with significant changes in TAPSE (P=0.008) and Tie index (P=0.008) at 24 hours.
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