Solvent Water in the Human Erythrocytes

Summary. The distribution of 5 anelectrolytes, urea, malonamide, glycol, glycerol and glucose added to defibrinated blood has been examined. In some experiments the serum was exchanged with 0.9 % NaCl. The methods used are described. Urea, glycerol and glucose are found in a highier concentration in the watery phase of the erythrocytes than in serum. Glycol is found in a somewhat lower concentration in the erythrocytes than in serum and malonamide in the same concentration in both. In experiments with 0.9 % NaCl in the outer solution, glycol as well as malonamide are found in higher concentration in the erythrocytes. It is assumed that the substances can be adsorbed to the colloids of serum and the erythrocytes but in a varying degree. The discrepancy between previous and the present experiments can partly be explained.