Why the study?
What factors influence long-term survival after aortic valve replacement in patients with different aortic valve pathologies?
What factors influence long-term survival after aortic valve replacement in patients with different aortic valve pathologies?
Different underlying aortic valve pathologies have distinct prognostic predictors after aortic valve replacement, supporting early surgical intervention.
In the aortic stenosis group, the left ventricular (LV) muscle mass index was a good parameter for predicting the prognosis. Associated mitral valve disease had no influence on long term survival after aortic valve replacement. In the aortic insufficiency group, associated mitral valve disease had a marked influence on the results of aortic valve replacement. In general, the aortic insufficiency group had less clinical improvement postoperatively than the aortic stenosis group. In the annuloaortic ectasia group, left ventricular enddiastolic pressure (LVEDP) might be the predictor to the prognosis. This group had the worst prognosis, of the three groups. Early operation should be considered for patients who have no, or only mild symptoms of, aortic valve disease.
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Shigenobu et al. (1980) studied this question.
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