Key result
Calcium-activated potassium channels, particularly the SK2 isoform, play a significant role in atrial repolarization and the pathophysiology of atrial fibrillation in experimental models.
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This editorial highlights emerging preclinical evidence that calcium-activated potassium channels (SK1 and SK2) play a significant role in atrial repolarization and may serve as novel, atrial-selective targets for AF therapy without ventricular proarrhythmic risk.
Stanley Nattel (2009) conducted an editorial in Atrial fibrillation. Calcium-activated potassium channels (SK2) was evaluated. Calcium-activated potassium channels, particularly the SK2 isoform, play a significant role in atrial repolarization and the pathophysiology of atrial fibrillation in experimental models.
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