Population
Normal and dystrophic chickens (anterior latissimus dorsi and patagialis muscles)
Comparison
Overloading for 35 days to induce hypertrophy vs Control normal and dystrophic chickens
Design
Preclinical
Follow-up
35 days
Authors
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No immediate clinical implications in dystrophy; leaves open whether overload-induced myosin shifts translate to mammalian models.
Overloading induces specific transitions in myosin phenotypes in both normal and dystrophic chicken muscles, though dystrophic muscles show some distinct baseline and adaptive differences.
Kennedy et al. (1991) studied this question.
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