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January 1, 1952British Journal of Radiology

II. The Response of Human Tissues to Radiation with Special Reference to Differentiation

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Authors

AGA. GlücksmannEmory University

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Implication

Histopathological analysis demonstrates altered cellular differentiation in human tissues following radiation, indicating variable radiobiological responses beyond cell killing.

Key Points

  • To evaluate how penetrating radiation influences the type, extent, and rate of cellular differentiation across normal and malignant human tissues.
  • Histological examination of tissue responses following exposure to penetrating radiation.
  • Comparative analysis of differentiation behavior in intermitotic secretory cells and postmitotic cells, including cervical squamous epithelium.
  • Penetrating radiation modifies both the specific mode and extent of cellular differentiation in exposed human tissues.
  • Irradiation of normal cervical squamous epithelium induces a relative increase in the rate of cell differentiation.

Cite This Study

A. Glücksmann (1952) studied this question.

synapsesocial.com/papers/6a886d0af9cabcdfeb4a6dd7https://doi.org/10.1259/0007-1285-25-289-38
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1II. The Influence of Systemic Factors on the Differentiation and Radiocurability of Cervical Cancers1956 · 15 citations
  2. 2Radiation Dermatitis: Radiation-Induced Effects on the Structural and Immunological Barrier Function of the Epidermis2024 · 73 citations
  3. 3Differential biological effect of low doses of ionizing radiation depending on the radiosensitivity in a cell line model2024
  4. 4The histopathologic basis for functional decrements in late radiation injury in diverse organs1976 · 51 citations
  5. 5Radiosensitivity and bystander response in X-ray irradiated tumour and normal epithelial cells of breast and prostate origin2026 · 1 citations