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February 12, 2014Critical CareOpen Access

Platelet mitochondrial membrane depolarization reflects disease severity in patients with sepsis and correlates with clinical outcome

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KGKatharina GründlerKlinik und Poliklinik für NuklearmedizinMAMatthias AngstwurmLMU KlinikumRHR. HilgeMünchen Klinik Harlaching

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Gründler et al. (2014) studied this question.

synapsesocial.com/papers/6a886db08e586ad1c8a558c3https://doi.org/10.1186/cc13724
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  1. 1APACHE II-A Severity of Disease Classification System1986 · 13,414 citations
  2. 2Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.1995 · 1,182 citations
  3. 3Survival and mitochondrial function in septic patients according to mitochondrial DNA haplogroup2012 · 27 citations