Answers are grounded in this paper and cite their sources.
A deep, self-folding cavitand responds to minor electronic differences between suitably sized adamantane guests. Binding constants range from <0.5 to 4000 M(-1) for guests as similar as 1-bromoadamantane and 1-cyanoadamantane. The barriers to guest exchange also vary up to 3 kcal mol(-1).
No takes yet. Share an insight, caveat, or question.
Hooley et al. (2008) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: