Effect of Dexmendetomidine on Emergence Agitation in Children Undergoing Surgeries using Sevoflurane- Randomized Controlled Observational Study

Background: Emergence agitation is one of the post-operative complication after paediatric surgeries. Its incidence ranging in literature from 10% to 80% 1 . Sevoflurane is very commonly used inhalational anaesthetic agent in induction and maintenance of anaesthesia. Incidence of emergence agitation may be high as 67% 2 when Sevoflurane is used. Study Design: Randomized controlled observational study Objective: Aim of this study was to assess the effect of DEXMENDETOMIDINE in prevention of emergence agitation in children (between 6 and 12 yrs of age) after undergoing various surgeries using Sevoflurane as an anaesthetic agent. Method: This study included 150 patients randomly classified into two groups. Group A underwent surgeries using sevoflurane as sole anaesthetic agent and Group B underwent surgeries using Sevoflurane with Dexmendetomidine intravenously. In Post operative stage all patients were assessed for emergence agitation using PAED 3 scale. Those having PAED score equal to or more than 16 were considered agitated. Result: Dexmendetomidine group had reduced emergence agitation (10.7%).