October 30, 2015Clinical Physiology and Functional Imaging

Blood flow‐restricted walking in older women: does the acute hormonal response associate with muscle hypertrophy?

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Why the study?

Does blood flow-restricted walking increase acute anabolic hormone levels and associate with muscle hypertrophy in older women?

Population

7 older women (age: 64 ± 2 years)

Comparison

Treadmill walking with blood flow restriction at… vs Treadmill walking without blood flow restriction…

Design

RCT, randomized crossover design

Follow-up

Immediately after and 15 minutes post-exercise

Authors

HOHayao OzakiTokai Gakuen University JLJeremy P. LoennekePreventive Cardiology TATakashi AbeRutgers, The State University of New Jersey

Discussion

Member takes

Implication

Hormonal elevations may not mediate BFR-walk hypertrophy in older women; challenges endocrine-centric models and directs research toward local mechanisms.

Structured PICO

Does blood flow-restricted walking increase acute anabolic hormone levels and associate with muscle hypertrophy in older women?

Population

7 older women (age: 64 ± 2 years)

Intervention

Treadmill walking with blood flow restriction (BFR-walk) at 45% of heart rate reserve for 20 min, wearing 5-cm cuffs on the proximal part of the upper legs

Comparator

Treadmill walking without blood flow restriction (CON-walk) at 45% of heart rate reserve for 20 min

Outcome

Acute changes in serum growth hormone, insulin, and noradrenaline, and their correlation with BFR-walk-induced muscle hypertrophysurrogate

Blood flow-restricted walking increases acute anabolic hormone levels in older women, but these hormonal changes do not appear to drive muscle hypertrophy.

Limitations

Preliminary results
Small sample size

Cite This Study

Ozaki et al. (2015) studied this question.

synapsesocial.com/papers/6a8877c6ceefe68dba4fcfc0 https://doi.org/10.1111/cpf.12312

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Ask AI

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Implication

Hormonal elevations may not mediate BFR-walk hypertrophy in older women; challenges endocrine-centric models and directs research toward local mechanisms.

Blood flow‐restricted walking in older women: does the acute hormonal response associate with muscle hypertrophy?

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Blood flow‐restricted walking in older women: does the acute hormonal response associate with muscle hypertrophy?

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider