Why the study?
Combined regional and general anaesthesia offers better intraoperative haemodynamic stability, prompting evaluation of whether adding intrathecal buprenorphine to general anaesthesia improves haemodynamic responses during laparoscopic appendicectomy.
Does intrathecal buprenorphine combined with general anaesthesia improve haemodynamic stability compared to general anaesthesia alone in patients undergoing laparoscopic appendicectomy?
Population
80 patients undergoing laparoscopic appendicectomy
Comparison
Combined general anaesthesia with intrathecal buprenorphine vs general anaesthesia alone
Design
Observational study using random sampling
Authors
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Intrathecal buprenorphine confers no hemodynamic benefit in this cohort; leaves open its role in randomized laparoscopic trials.
Does intrathecal buprenorphine combined with general anaesthesia improve haemodynamic stability compared to general anaesthesia alone in patients undergoing laparoscopic appendicectomy?
The addition of intrathecal buprenorphine to general anaesthesia provides little advantage in preventing the haemodynamic stress response during laparoscopic appendicectomy.
Azim Palayil (2021) studied this question.
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