Area-Level Deprivation and Overall and Cause-Specific Mortality: 12 Years’ Observation on British Women and Systematic Review of Prospective Studies

María T. Sánchez-Santos; Marco Mesa‐Frias; Minkyoung Choi; Eveline Nüesch; Ángel Asúnsolo; Antoinette Amuzu; George Davey Smith; Shah Ebrahim; David Prieto‐Merino; Juan P. Casas

doi:10.1371/journal.pone.0072656

September 24, 2013PLoS ONEOpen Access

Area-Level Deprivation and Overall and Cause-Specific Mortality: 12 Years’ Observation on British Women and Systematic Review of Prospective Studies

View Full Paper

Ask AI

Bookmark

Share

Why the study?

Does area-level deprivation increase the risk of overall and cause-specific mortality?

Structured PICO

Does area-level deprivation increase the risk of overall and cause-specific mortality?

P

Population

4,286 women from the British Women's Heart Health Study (BWHHS) recruited at 1999-2001, and a meta-analysis of 20 published prospective studies.

I

Intervention

Higher area-level deprivation (measured by Index of Multiple Deprivation [IMD] or bottom tertile of deprivation)

C

Comparator

Lower area-level deprivation (least deprived; top tertile)

O

Outcome

Overall mortality and cause-specific mortality (including vascular and respiratory deaths)hard clinical

Area-level deprivation is associated with increased overall and cause-specific mortality, an effect that is partially mediated by health behaviors and biological factors.

Implication

Area deprivation linked to modestly higher mortality after adjustment; extends social determinants evidence but leaves causal mechanisms and interventions open.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Sánchez-Santos et al. (2013) studied this question.

synapsesocial.com/papers/6a88f2a38513b156087b3fda https://doi.org/10.1371/journal.pone.0072656

View Full Paper

Ask AI

Bookmark

Share

Area-Level Deprivation and Overall and Cause-Specific Mortality: 12 Years’ Observation on British Women and Systematic Review of Prospective Studies

Structured PICO

Implication

Discussion

Cite This Study

Area-Level Deprivation and Overall and Cause-Specific Mortality: 12 Years’ Observation on British Women and Systematic Review of Prospective Studies

Structured PICO

Implication

Discussion

Cite This Study

Keep reading

Keep reading