Why the study?
Obstructive sleep apnea is a known risk factor for AF and stroke, but its association with an increased cardioembolic risk in patients with AF needed exploration.
Is obstructive sleep apnea-related hypoxia associated with increased cardioembolic risk in patients with atrial fibrillation?
Is obstructive sleep apnea-related hypoxia associated with increased cardioembolic risk in patients with atrial fibrillation?
In patients with atrial fibrillation and obstructive sleep apnea, greater severity of sleep-related hypoxia is associated with a higher CHA2DS2-VASc score, suggesting an increased risk for cardioembolic complications.
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Nocturnal hypoxia may refine cardioembolic risk assessment in AF; leaves open whether OSA treatment reduces stroke events.
Pengo et al. (2020) studied this question.
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