Why the study?
Does a high NaCl diet alter myogenic tone and flow-induced dilation in resistance arteries of normotensive rats?
Population
Normotensive Wistar Kyoto Rats
Comparison
High NaCl diet (8%) vs Normal NaCl diet (0.4%)
Design
Preclinical
Authors
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High NaCl impairs resistance artery tone and dilation in normotensive rats; leaves open translation to human salt sensitivity or dietary guidance.
Does a high NaCl diet alter myogenic tone and flow-induced dilation in resistance arteries of normotensive rats?
High NaCl intake alters flow and pressure mechanosensing processes in resistance arteries of normotensive rats, involving the induction of cyclooxygenase-2.
Matrougui et al. (2001) studied this question.
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