Why the study?
Does mental arithmetic or lower body negative pressure affect the accuracy of forearm blood flow ratio in detecting unilateral increases in forearm blood flow in healthy male volunteers?
Does mental arithmetic or lower body negative pressure affect the accuracy of forearm blood flow ratio in detecting unilateral increases in forearm blood flow in healthy male volunteers?
Forearm blood flow ratio may underestimate unilateral increases in forearm blood flow during simultaneous mental arousal.
AIMS: To determine the accuracy of forearm blood flow (FBF) ratio (flow in infused arm/flow in control arm) to detect unilateral increases in forearm blood flow. METHODS: In nine healthy male volunteers, we measured the effect of infusion of saline into the brachial artery at a rate of 2 ml/100 ml forearm min-1 on FBF ratio during control, mental arithmetic (MAR) and lower body negative pressure (LBNP) at -40 mmHg. RESULTS: Saline infusion increased FBF ratio from baseline by 115.9+/-17.4, 82.0+/-19.0 and 159.6+/-53.3% for control, MAR and LBNP, respectively (P<0.05 for MAR vs control). CONCLUSIONS: FBF ratio may underestimate unilateral increases in forearm blood flow during simultaneous mental arousal.
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Rongen et al. (1999) studied this question.
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