Effects of Hydrostatic Pressures Upon the Excitability, the Recovery, and the Potential Sequence of Frog Nerve

The study of nerves by means of the potential changes which accompany activity has thus far proved a most precise and fruitful approach to in-vestigations of nerve function. The electrophysi-ologist, however, recognizes the correctness of the dictum--"You cannot determine a process from a potential. " (Gasser, 1933). But since physiologists desire most of all to know and to understand the processes underlying biological activity, the inves-tigator of nerve potentials has had recourse to a procedure general to the scientific method, and has to some extent circunwented this difficulty in a variety of ways. By correlating excitability data with the potentials, by studies of the modifications in the potential picture produced through ionic