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September 3, 1996Proceedings of the National Academy of SciencesOpen Access

A dynamic assembly of diverse transcription factors integrates activation and cell-type information for interleukin 2 gene regulation.

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Authors

EREllen V. RothenbergCalifornia Institute of TechnologySWSusan B. WardCalifornia Institute of Technology

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Rothenberg et al. (1996) studied this question.

synapsesocial.com/papers/6a891cfc3d6e0fcd7a28c0ebhttps://doi.org/10.1073/pnas.93.18.9358
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1IL-2 promoter-driven lacZ expression as a monitoring tool for IL-2 expression in primary T cells of transgenic mice1994 · 36 citations
  2. 2Transcriptional activation by protein-induced DNA bending: evidence for a DNA structural transmission model.1996 · 101 citations
  3. 3Promoter Region of Interleukin-2 Gene Undergoes Chromatin Structure Changes and Confers Inducibility on Chloramphenicol Acetyltransferase Gene During Activation of T Cells1986 · 67 citations
  4. 4Constitutive and metal-inducible protein:DNA interactions at the mouse metallothionein I promoter examined by in vivo and in vitro footprinting.1988 · 176 citations
  5. 5Novel NFAT Sites That Mediate Activation of the Interleukin-2 Promoter in Response to T-Cell Receptor Stimulation1995 · 262 citations