What question did this study set out to answer?

To determine the diagnostic accuracy, sensitivity, and complication rates of percutaneous CT-guided fine-needle aspiration biopsy (FNAB) for small pulmonary lesions measuring 1.0 cm or less.

December 1, 2002Radiology

CT-guided Percutaneous Fine-Needle Aspiration Biopsy of Small (≤1-cm) Pulmonary Lesions

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Authors

SKSavitri KrishnamurthyThe University of Texas MD Anderson Cancer Center LBLyle D. BroemelingEngineering Associates (United States)SGSanjay GuptaThe University of Texas MD Anderson Cancer Center

Discussion

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Implication

Observational study reveals high diagnostic accuracy for CT-guided fine-needle aspiration biopsy in small pulmonary nodules, indicating strong utility despite frequent pneumothorax.

Key Points

To determine the diagnostic accuracy, sensitivity, and complication rates of percutaneous CT-guided fine-needle aspiration biopsy (FNAB) for small pulmonary lesions measuring 1.0 cm or less.
Evaluated 61 patients (mean age 61.3 years; 57 with known primary malignancy) with pulmonary nodules ≤1.0 cm undergoing CT-guided transthoracic FNAB with immediate cytopathological review.
Stratified diagnostic performance by lesion diameter (0.5–0.7 cm vs. 0.8–1.0 cm) and lesion depth relative to the pleural surface (subpleural ≤1.0 cm vs. deeper >1.0 cm), while recording procedural complications.
Among 57 evaluable patients, FNAB achieved an overall sensitivity of 82% (32 of 39), specificity of 100% (18 of 18), and diagnostic accuracy of 88% (50 of 57).
Lesions measuring 0.8–1.0 cm demonstrated higher diagnostic yield (sensitivity 88%, accuracy 92%) than lesions measuring 0.5–0.7 cm (sensitivity 50%, accuracy 70%).
Pneumothorax developed in 62% of patients (38 of 61), with 31% (19 of 61) requiring chest tube placement (thoracostomy).

Cite This Study

Krishnamurthy et al. (2002) studied this question.

synapsesocial.com/papers/6a891fd5789d3eba981a30d1 https://doi.org/10.1148/radiol.2253011465

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Implication

Observational study reveals high diagnostic accuracy for CT-guided fine-needle aspiration biopsy in small pulmonary nodules, indicating strong utility despite frequent pneumothorax.

CT-guided Percutaneous Fine-Needle Aspiration Biopsy of Small (≤1-cm) Pulmonary Lesions

Discussion

Member takes

Implication

Key Points

Cite This Study

CT-guided Percutaneous Fine-Needle Aspiration Biopsy of Small (≤1-cm) Pulmonary Lesions

Discussion

Member takes

Implication

Key Points

Cite This Study

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