Why the study?
Does carotid artery stenting without angioplasty prevent hemodynamic depression in high-risk patients with severe carotid artery disease before coronary revascularization surgery?
Does carotid artery stenting without angioplasty prevent hemodynamic depression in high-risk patients with severe carotid artery disease before coronary revascularization surgery?
Carotid artery stenting without angioplasty prior to cardiac surgery appears to be a safe strategy that avoids hemodynamic depression in patients with coexisting severe carotid and coronary artery disease.
Hypothesis-generating that stenting without angioplasty avoids hemodynamic depression before cardiac surgery; leaves open safety and efficacy in prospective studies.
Hemodynamic depression (HD) is a frequent complication related to carotid endartherectomy or carotid artery stenting (CAS), often not well tolerated in patients with coronary artery disease. The purpose of this study is to assess whether CAS without angioplasty is beneficial in patients with severe carotid artery disease before coronary revascularization surgery (CABG) regarding the occurrence of HD. Between October 2002 and August 2006, 39 CAS were performed in 35 patients before cardiac surgery. Outcome measures, including periprocedural and 30-day post stenting and cardiac surgery complications, were assessed. Twenty-seven patients underwent CABG and eight combined CABG and valve replacement. During or immediately after CAS there was no episode of bradycardia or hypotension necessitating medical treatment. In the period between CAS-CABG, there was no case of HD. We also found no myocardial infarction. There were five neurological complications, two of them in the period between CAS-CABG (one transitory ischemic attack (TIA) and one minor stroke) and three after CABG (one TIA and two strokes). Three of them were discharged symptom-free. CAS without angioplasty can be a safe alternative to treat patients with coexistence of carotid and cardiac disease, since does not produce hemodynamic depression, therefore diminishing the cardiac complications.
No takes yet. Share an insight, caveat, or question.
Rabellino et al. (2010) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:
More on Coronary artery diseaseMore from Minimally Invasive Therapy & Allied Technologies