Why the study?
Does warfarin therapy increase the risk of bleeding complications in patients undergoing cutaneous surgery, and does perioperative INR predict this risk?
Population
157 patients undergoing cutaneous surgery, comprising 65 patients on warfarin and 92 nonwarfarinized controls
Comparison
Warfarin therapy continued during surgery vs No warfarin therapy (nonwarfarinized controls)
Design
Cohort
Authors
Loading...
Warfarin associated with higher bleeding risk after cutaneous surgery despite INR <2.6; leaves open whether perioperative INR reliably predicts complications.
Does warfarin therapy increase the risk of bleeding complications in patients undergoing cutaneous surgery, and does perioperative INR predict this risk?
Patients on warfarin undergoing cutaneous surgery have a small but significantly increased risk of postoperative bleeding that is poorly predicted by perioperative INR levels.
Blasdale et al. (2008) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: