November 1, 2000Anesthesia & Analgesia
Part II: Total Episode Costs in a Randomized, Controlled Trial of the Effectiveness of Four Anesthetics
Why the study?
Do propofol and sevoflurane reduce total episode costs compared to thiopental and isoflurane in adults undergoing elective inpatient general surgery?
Population
500 adults undergoing elective inpatient general surgery
Comparison
Propofol and sevoflurane (newer anesthetics) vs Thiopental and isoflurane (older anesthetics)
Design
RCT, Randomly assigned to one of four anesthetic regimens
Follow-up
3 months
Authors
Discussion
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Implication
Propofol/sevoflurane regimens offer no cost advantage; confirms economic equivalence with thiopental/isoflurane for elective inpatient surgery.
Structured PICO
Do propofol and sevoflurane reduce total episode costs compared to thiopental and isoflurane in adults undergoing elective inpatient general surgery?
P
Population
500 adults undergoing elective inpatient general surgery
I
Intervention
Propofol and sevoflurane (newer anesthetics)
C
Comparator
Thiopental and isoflurane (older anesthetics)
O
Outcome
Total episode costs of hospitalization
Propofol and sevoflurane do not offer significant economic advantages over thiopental and isoflurane for adults undergoing elective inpatient surgery.
Limitations
- Not powered to sufficiently show differences in intensive care unit admission or other uncommon outcomes
- Patient willingness-to-pay and satisfaction were not directly measured
Cite This Study
Jackson et al. (2000) studied this question.