Population
Pregnancy sera
Design
Cross-sectional
Follow-up
Up to third trimester
Authors
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May inform hCG assay interpretation in early pregnancy; hypothesis-generating for two-phase dimer regulation, needing longitudinal validation.
The study proposes a two-phase regulation of hCG dimer formation during pregnancy, with alpha-subunit limiting early on and beta-subunit limiting later.
Cole et al. (1984) studied this question.
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