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August 20, 2021Clinical Hemorheology and Microcirculation

Coronary venous therapy to improve microvascular dysfunction

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Why the study?

Understanding of coronary microvascular disease remains incomplete with no specific therapy available, and the role of the coronary venous circulation in regulating coronary resistances is largely unexplored.

Do coronary sinus interventions improve coronary perfusion in patients with coronary microvascular disease?

Design

Review paper

Authors

Tommaso Gori
Tommaso GoriInterventional / Structural Cardiology

Discussion

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Implication

Coronary sinus interventions should not yet alter management of ischemic heart disease; leaves open their role pending controlled trials.

Structured PICO

Do coronary sinus interventions improve coronary perfusion in patients with coronary microvascular disease?

P
Population
Patients with acute and chronic coronary microvascular disease and ischaemic heart disease
I
Intervention
Coronary sinus interventions (surgical and catheter-based)

This review highlights the potential of coronary sinus interventions to treat ischemic heart disease and coronary microvascular dysfunction by modulating coronary venous pressure.

Cite This Study

Tommaso Gori (2021) studied this question.

synapsesocial.com/papers/6a892757a997fa18eea5eb6fhttps://doi.org/10.3233/ch-219103
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Reconsidering the back door approach by targeting the coronary sinus in ischaemic heart disease2016 · 22 citations
  2. 2Coronary Sinus Interventions: From Concept to Clinics1987 · 35 citations
  3. 3Coronary venous retroperfusion: an old concept, a new approach2008 · 31 citations
  4. 4Peripheral microvascular dysfunction is also present in patients with ischemia and no obstructive coronary artery disease (INOCA)2021 · 11 citations
  5. 5Intracoronary Hemodynamic Effects of Pressure‐Controlled Intermittent Coronary Sinus Occlusion (PICSO): Results from the First‐In‐Man Prepare PICSO Study2012 · 35 citations