Analysis Of Cardiopulmonary Bypass Duration Towards Neutrofil Limfosite Ratio On Patients After Coronary Artery Bypass Grafting In Cardiac Surgical Intensive Care Unit At Adam Malik Hospital Medan

Background: The aim of this study was to investigate the prognostic role of the neutrophil to lymphocyte ratio (NLR) in patients undergoing Coronary Artery Bypass Grafting (CABG) with cardiopulmonary bypass (CPB). Methods: A retrospective cohort study of 91 patients who underwent CABG with CPB in the Cardiac Surgical ICU , Haji Adam Malik Hospital, Medan from January 2019 to December 2019 was conducted. All perioperative clinical data, including CPB time, Aortic cross clamp (AOX) time, neutrophil count, lymphocyte count, were collected retrospectively. Retrospective study was performed to compared NLR in patients with prolonged CPB Time. The prognostic value of NLR and its association duration of intensive care unit (ICU) stay were analyzed. Results: Leucocytes count, NLR, and CRP were significantly increased post-operative compared with preoperative (p < 0.05). The increased post-operative levels of NLR were significantly associated with prolonged CPB time (p < 0.05). Strong correlation (r: 0.505) between CPB time and NLR were reported. The increased post-operative levels of NLR were also significantly associated with prolonged post-operative cardiac ICU stay (p < 0.05). Conclusion: Increased post-operative NLR followed by cardiac surgery with prolong CPB time in CABG patients was associated with a longer duration of an ICU stay.