Key result
Preoperative neutrophil-lymphocyte ratio > 2.5 was significantly associated with a higher rate of prolonged ICU stay compared to NLR < 2.5 (91.7% vs 58.4%, p<0.001) after CABG.
Why the study?
NLR is an inexpensive, accessible inflammatory biomarker known to predict poor outcomes in many diseases, but its relationship with post-CABG outcomes needed evaluation.
Does an elevated preoperative neutrophil-lymphocyte ratio (NLR > 2.5) predict prolonged ICU and hospital stay in patients undergoing elective CABG?
Cross-Sectional (n=137)
No
Does an elevated preoperative neutrophil-lymphocyte ratio (NLR > 2.5) predict prolonged ICU and hospital stay in patients undergoing elective CABG?
Answers are grounded in this paper and cite their sources.
An elevated preoperative neutrophil-lymphocyte ratio (>2.5) is associated with significantly prolonged ICU and hospital stays following elective CABG, suggesting its utility as a simple, inexpensive prognostic biomarker.
Neutrophil-lymphocyte ratio (NLR) is an inexpensive and easily accessible inflammatory biomarker. Studies have shown the ability of NLR to predict poor outcome in many diseases. This study aimed to determine the relationship between NLR and cardiovascular risk factors, and duration of ICU and hospital stay in post CABG patients. 137 patients who underwent CABG between 2013 and 2017 with available preoperative neutrophil and lymphocyte counts were included in the study. NLR was found to be increased in patients who had prolonged intensive care unit (ICU) stay and hospital/ ward stay. Thus NLR can potentially be used to predict worse outcome.Keywords: Neutrophil-lymphocyte ratio; coronary artery bypass graft (CABG); mortality; length of stay (maximum 4 keywords) eISSN: 2398-4287 © 2019. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.DOI: https://doi.org/10.21834/e-bpj.v4i10.1628
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Kamal et al. (2019) conducted a cross-sectional in Coronary Artery Disease (undergoing CABG) (n=137). Preoperative Neutrophil-Lymphocyte Ratio (NLR) > 2.5 vs. Preoperative NLR < 2.5 was evaluated on Prolonged ICU stay (>3 days) (p=<0.001). Preoperative neutrophil-lymphocyte ratio > 2.5 was significantly associated with a higher rate of prolonged ICU stay compared to NLR < 2.5 (91.7% vs 58.4%, p<0.001) after CABG.
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