Why the study?
Does combined epidural and general anaesthesia alter intraoperative cardiovascular changes and postoperative complications in patients undergoing elective abdominal aortic surgery?
Does combined epidural and general anaesthesia alter intraoperative cardiovascular changes and postoperative complications in patients undergoing elective abdominal aortic surgery?
Combining epidural with general anaesthesia alters intraoperative cardiovascular management but does not significantly affect postoperative outcomes compared to general anaesthesia alone in abdominal aortic surgery.
CEGA alters intraoperative vasopressor and GTN use without reducing complications; reinforces no outcome benefit versus general anaesthesia alone in aortic surgery.
Fifty patients undergoing elective abdominal aortic surgery were randomised to receive either combined epidural and general anaesthesia and postoperative epidural analgesia (CEGA) or general anaesthesia and postoperative intravenous morphine infusion (GA). Prospective data was collected in order to compare the two groups. This included intraoperative cardiovascular changes and postoperative complications. The use of intraoperative vasopressors was significantly higher in the CEGA group (P < 0.01) but the use of intravenous glyceryl trinitrate was significantly lower (P < 0.01). There was no significant difference between groups in regard to blood loss, volume replacement or in the number of patients requiring postoperative ventilation. Two patients in the CEGA group died postoperatively compared to one in the GA group (not significant). There was no significant difference between groups in the total number or type of postoperative complications. Combining epidural anaesthesia with general anaesthesia altered intraoperative cardiovascular management but did not affect postoperative outcome.
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Davies et al. (1993) studied this question.
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