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May prompt evaluation for secondary causes in lone AF; hypothesis-generating and should not yet change practice.
Atrial fibrillation, usually considered a benign arrhythmia, recognizes several aetiologies: not only sctructural cardiopathies, but also other diseases, drugs intake or post-operative courses. Sometimes it can occur in absence of apparente cause. More and more frequently it is usual to consider this arrhythmia like a marker of pathological unknown situation; therefore, also patients with “lone atrial fibrillation” should be submitted to surveys in order to find probable associated causes.
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Delsignore et al. (2015) studied this question.
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