Key result
AF imposes significant morbidity and mortality regardless of symptoms, while young lone AF risks remain debated.
Why the study?
Atrial fibrillation is the most common cardiac arrhythmia with significant morbidity and mortality, but risk in young patients with lone AF remains inconclusive.
Atrial fibrillation is a common arrhythmia with significant morbidity and mortality, placing a heavy burden on healthcare services.
Lone AF in young patients may harbor overlooked risks; leaves open optimal long-term management strategies.
Atrial fibrillation is the most common cardiac arrhythmia in everyday clinical practice, and has a significant morbidity and mortality related to it, either directly or indirectly. Atrial fibrillation results in a heavy burden on NHS services, in terms of both in-patient admissions, and out-patient care. Atrial fibrillation can be symptomatic or asymptomatic, yet morbidity and mortality are not much different in relation to symptom status. However, young patients with ‘lone AF’ (i.e. AF without ‘overt’ structural heart disease, as defined by essentially normal clinical history and examination, electrocardiogram, chest X-ray, and, in more recent series, the ECG) are often considered as being ‘at low risk’, although recent data have been less conclusive on this aspect.
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Lip et al. (2007) conducted a review in Atrial fibrillation. Atrial fibrillation imposes a significant morbidity, mortality, and healthcare burden regardless of symptom status, while the risk profile of lone AF in young patients remains debated.
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