Why the study?
Does graded renal nerve stimulation affect renal venous outflow and urinary excretion of catecholamines in anesthetized dogs?
Does graded renal nerve stimulation affect renal venous outflow and urinary excretion of catecholamines in anesthetized dogs?
Renal nerves release both dopamine and norepinephrine, but urinary catecholamine excretion is a poor indicator of intrarenal catecholamine release.
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High-level RNS boosts intrarenal catecholamine release in dogs; leaves open urinary biomarker validity and human translation for renal denervation.
Kopp et al. (1983) studied this question.
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