Why the study?
Does controlled hypotension reduce blood loss and transfusion needs during major surgical procedures?
Population
Patients undergoing defined major surgical procedures
Comparison
Controlled hypotension vs Moderate hypotension
Design
Review
Authors
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Extreme hypotension (MAP <60 mmHg) should be avoided; leaves open optimal targets for controlled hypotension in major surgery.
Does controlled hypotension reduce blood loss and transfusion needs during major surgical procedures?
Controlled hypotension is effective for reducing blood loss during major surgery, but extreme hypotension (MAP < 60 mmHg) should be avoided due to increased cardiovascular risks without additional blood-sparing benefits.
Alf Sollevi (1988) studied this question.
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