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Albumin is derived from plasma and it is the most abundant protein in plasma, which is an ideal material for the preparation of nanoparticles because of its good biocompatibility, noncytotoxicity, nonimmunogenicity, biodegradability, and so on. Albumin amplifies the targeting of drugs, brings down the deadliness of free drugs, and amplifies water solubility of free drugs. The methods of preparation of albumin nanoparticles exhibit benefits and drawbacks due to contrasts in principles and preparation conditions.
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Samaddar et al. (2023) studied this question.
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