SummaryBiochemical investigations of costal cartilage and intact skin from scorbutic guinea pigs revealed the content of collagen, as represented by the content of hydroxyproline, to be unchanged in both tissues.The content of hexuronic acid, a component of the acid mucopolysaccharides of the connective tissue, determined by the carbazole and orcinol methods, was found to be significantly reduced in intact skin, but unchanged in costal cartilage.The content of hexosamine is not significantly different in the tissues examined, but tends towards a reduction.
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Bendt Kirchheiner (1965) studied this question.
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