Visceral Adiposity, Not Abdominal Subcutaneous Fat Area, Is Associated With an Increase in Future Insulin Resistance in Japanese Americans
Why the study?
Does greater visceral adiposity predict future insulin resistance in nondiabetic Japanese Americans?
Population
306 nondiabetic Japanese Americans
Comparison
Visceral adiposity vs Other adipose depots
Design
Cohort
Follow-up
10-11 years
Authors
Discussion
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Member takes
Implication
Visceral adiposity was associated with future insulin resistance in nondiabetic Japanese Americans; hypothesis-generating and requires prospective confirmation before clinical application.
Structured PICO
Does greater visceral adiposity predict future insulin resistance in nondiabetic Japanese Americans?
P
Population
306 nondiabetic Japanese Americans
I
Intervention
Visceral adiposity (intra-abdominal fat area at the umbilicus level measured by CT)
C
Comparator
Other adipose depots (abdominal subcutaneous fat area, total subcutaneous fat area, total fat area, BMI, or waist circumference)
O
Outcome
Insulin resistance evaluated by homeostasis model assessment for insulin resistance (HOMA-IR) at 10-11 yearssurrogate
Greater visceral adiposity, rather than subcutaneous fat or overall BMI, is an independent predictor of future insulin resistance.
Cite This Study
Hayashi et al. (2008) studied this question.