Why the study?
Does the presence of cardiovascular risk factors reduce the response to PAH drug therapy in patients with pulmonary arterial hypertension?
Population
146 consecutive incident patients with pulmonary arterial hypertension between January 1, 2008, and July 15…
Comparison
PAH drug therapy in patients with at least one… vs PAH drug therapy in patients with no…
Design
Cohort
Follow-up
30 months
Authors
Loading...
Cardiovascular risk factors may blunt PAH treatment response; hypothesis-generating finding leaves open whether they should alter therapy selection or trial eligibility.
Does the presence of cardiovascular risk factors reduce the response to PAH drug therapy in patients with pulmonary arterial hypertension?
The presence of cardiovascular risk factors in patients with pulmonary arterial hypertension predicts a reduced clinical response to PAH-specific drug therapies, independent of age.
Charalampopoulos et al. (2014) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: