Atracurium administration during surgery can lead to severe bradycardia, highlighting the need for full electrocardiographic monitoring and potential prophylactic atropine.
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Atracurium may induce severe bradycardia; case reports leave open need for routine monitoring or prophylaxis.
Four cases of severe bradycardia developed during surgery in patients given the neuromuscular blocking agent atracurium as part of the anaesthesia. In all cases sinus rhythm was restored by giving intravenous atropine. It is recommended that in all operations in which vagal stimulation is expected patients should be given atropine as part of the premedication or induction sequence and should undergo full electrocardiographic monitoring during surgery.
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M L Carter (1983) studied this question.
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