This case report highlights that long-lasting severe pressure overload and subtle myocardial ischemia from diffuse supravalvular aortic stenosis can lead to left ventricular apical aneurysm.
Apical aneurysm may occur in supravalvular AS without CAD or HOCM; first report leaves open prevalence and causality.
Congenital nonfamilial supravalvular aortic stenosis (SVAS) is relatively rare, its diffuse type being the least common. We present a 30-year-old woman with diffuse SVAS complicated with left ventricular apical aneurysm. We believe that subtle left ventricular myocardial ischemia or infarction and long-lasting severe pressure overload to the apical chamber caused LV apical aneurysm in our case. Acquired LV apical aneurysm secondary to supravalvular aortic stenosis, in the absence of atherosclerotic coronary artery disease and hypertrophic obstructive cardiomyopathy, has not been described before.
No takes yet. Share an insight, caveat, or question.
Heper et al. (2005) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: