Why the study?
Certain cytokines and proteins regulate energy homeostasis and represent potential targets against adipose tissue fibrosis and insulin resistance, prompting a focus on the regulatory mechanisms and mediators of adipose remodeling and their clinical relevance.
Design
Review
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Adipose fibrosis may mediate obesity-related metabolic dysfunction; hypothesis-generating for ECM-targeted research.
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Li et al. (2021) studied this question.
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