Population
Purified F-actin, unpurified actin preparations, and mixtures of actin, tropomyosin, and troponin
Comparison
Addition of a mixture of tropomyosin and… vs Purified F-actin alone, or purified F-actin with…
Design
Preclinical
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Supports troponin as source of thin-filament periodicity; leaves open translation to human cardiac sarcomere function.
The cross-striation in thin myofilaments can be attributed to the location of the troponin complex at regular intervals along the filaments.
A 1973 study studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: