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One of the limiting factors of the fluoride-enamel reaction is the close proximity of the enamel crystals. We proposed to loosen the structure of enamel somewhat to cause a favorable reaction with fluoride. The final phase of the process, for which the name enamel conditioning is proposed, is the retightening of the enamel structure (triggered by fluoride ions) and the incorporation of fluoride into the enamel crystals.
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Katz et al. (1971) studied this question.
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