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Sting like a bee: Nanoarrays of infectious virus particles, encoded with EGFP, are patterned by dip-pen nanolithography and exposed to a solution of cells. Upon infection, infected cells produce the EGFP protein, generating a green fluorescence signal that allows one to monitor the cellular infection process in real time (as seen in the optical image). These results suggest that antibody-immobilized virus particles retain their biological activity. Scale bar: 35μm.
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Vega et al. (2007) studied this question.
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