Sialic acid in normal and arthritic human synovial fluids

The authors report careful and significant studies of the synovial fluid concentrations of sialic acid, a term which is applied to a group of related compounds first isolated from saliva. The nature of such compounds is reviewed. Since available methods for determining sialic acid are not specific, two colorimetric procedures were applied. A critical discussion of methodology is presented. Increased concentrations of sialic acid were observed in both the synovial fluids and sera of rheumatoid patients. Le autores reporta meticulose e significative studios in re le concentration—in le fluido synovial—del si‐appellate acido sialic. Iste termino es applicate a un gruppo de inter‐relationate compositos primo isolate ab specimens de saliva. Le natura de tal compositos es passate in revista. Viste que le nunc disponibile methodos pro determinar acido sialic non es specific, duo technicas colorimetric esseva applicate. Es presentate un discussion critic del methodologia. Augmentate concentrationes de acido sialic esseva observate in le fluidos synovial e in le seros de patientes rheumatoide.