THE relation of chronic discoid lupus erythematosus to systemic lupus erythematosus has always been controversial. Studies reporting a frequent occurrence of clinical and laboratory abnormalities have led some authors to conclude that there is a high incidence of systemic involvement in patients with chronic discoid lupus and that the two diseases may represent different manifestations of the same conditio,.1 , 2 However, the lack of suitable control groups in these studies makes the data difficult to evaluate.To clarify this problem we have studied 65 patients with chronic discoid lupus erythematosus and 65 patients with other dermatologie disorders matched for age, sex . . .
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Rothfield et al. (1963) studied this question.
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