Why the study?
What are the optimal treatment options for children with nonrhabdomyosarcoma soft tissue sarcoma?
What are the optimal treatment options for children with nonrhabdomyosarcoma soft tissue sarcoma?
Wide local excision is currently the best curative option for pediatric nonrhabdomyosarcoma soft tissue sarcoma, though further studies are needed to optimize adjuvant therapies.
Supports wide local excision for pediatric NRSTS; leaves open optimal adjuvant strategies pending prospective trials.
Nonrhabdomyosarcoma soft tissue sarcomas account for approximately 40% of all soft tissue sarcomas in children. Although these tumors are typically grouped together, individual tumor types with different biological characteristics have been found that may impact on the optimal therapy for each type of sarcoma in the future. Most of the current information regarding this tumor comes from the adult literature. Wide local excision appears to provide the best chance of cure. Future studies are needed to determine which adjuvant therapies are most useful in improving local control and overall survival in the different subsets of patients.
No takes yet. Share an insight, caveat, or question.
Arnold C. Paulino (2004) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: