Femur amputation without further treatment resulted in a disease-free state at 9 months in a rare case of primary leiomyosarcoma of bone.
Supports amputation alone in rare primary bone leiomyosarcoma; leaves open optimal management pending larger series.
A case of primary leiomyosarcoma of bone in the femur of an 18-year-old girl is described. Light and electron microscopy showed characteristic changes with cytoplasmic myofilaments, dense bodies, pinocytic vesicles and basal lamina fragments. Clinically, the patient is well and without evidence of tumor 9 months after the femur amputation without further treatment.
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Overgaard et al. (1977) studied this question.
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