What question did this study set out to answer?

To evaluate the spectrum, risk factors, and diagnostic performance of Western screening guidelines for retinopathy of prematurity in infants weighing greater than 1250 grams at birth.

January 1, 2007Indian Journal of OphthalmologyOpen Access

Retinopathy of prematurity in Asian Indian babies weighing greater than 1250 grams at birth: Ten year data from a tertiary care center in a developing country

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Authors

MDMangatR DograPost Graduate Institute of Medical Education and Research AVAnand VinekarAll India Institute of Medical Sciences TSTiakumzuk SangtamNational University of Singapore

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Implication

Retrospective case series demonstrates severe retinopathy of prematurity in heavier infants, highlighting the inadequacy of Western screening criteria in developing nations.

Key Points

To evaluate the spectrum, risk factors, and diagnostic performance of Western screening guidelines for retinopathy of prematurity in infants weighing greater than 1250 grams at birth.
Retrospective, non-randomized observational case series analyzing 10-year records from 275 eyes of 138 infants diagnosed with retinopathy of prematurity and birth weights exceeding 1250 grams.
Assessed demographic and systemic risk factors using Chi-square tests, unpaired t-tests, ANOVA, and multivariate logistic regression, alongside sensitivity analyses of American and British screening criteria.
Threshold or worse retinopathy of prematurity developed in 124 of 275 eyes (45.1%), occurring across a mean birth weight of 1533.9 g (range: 1251–2750 g) and mean gestational age of 30.9 weeks (range: 26–35 weeks).
Significant independent risk factors for threshold or worse disease were outborn delivery status (P < 0.001), sepsis (P = 0.007), and exchange transfusion (P = 0.003).
American and British screening guidelines demonstrated sensitivities of only 82.4% and 77.4%, respectively, for identifying threshold or worse retinopathy of prematurity.

Cite This Study

Dogra et al. (2007) studied this question.

synapsesocial.com/papers/6a895a8b5edafe343d92d87c https://doi.org/10.4103/0301-4738.33817

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Implication

Retrospective case series demonstrates severe retinopathy of prematurity in heavier infants, highlighting the inadequacy of Western screening criteria in developing nations.

Retinopathy of prematurity in Asian Indian babies weighing greater than 1250 grams at birth: Ten year data from a tertiary care center in a developing country

Discussion

Member takes

Implication

Key Points

Cite This Study

Retinopathy of prematurity in Asian Indian babies weighing greater than 1250 grams at birth: Ten year data from a tertiary care center in a developing country

Discussion

Member takes

Implication

Key Points

Cite This Study

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