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August 22, 2026Emergency Care and MedicineOpen Access

Standardized Prehospital Extracorporeal Cardiopulmonary Resuscitation (ECPR) Protocol for Refractory Out-of-Hospital Cardiac Arrest: The PrehospECPR-GOKVI Operational Framework

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Authors

CSCsaba SáriPÓPéter ÓváriAAAbdelkrim Ahres

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Overview

Protocol report outlines a prehospital extracorporeal resuscitation framework for refractory cardiac arrest, indicating structured criteria can streamline emergency cannulation.

Key Points

  • To establish a standardized operational protocol for delivering prehospital extracorporeal cardiopulmonary resuscitation to eligible patients with refractory out-of-hospital cardiac arrest.
  • Designed a standardized pathway utilizing a dedicated two-person team (physician and paramedic) equipped with point-of-care ultrasound, a mobile oxygenator, and a pre-primed venoarterial extracorporeal membrane oxygenation circuit.
  • Established strict inclusion criteria (witnessed arrest, age <50 years, refractory arrest ≥15 minutes, ECMO flow feasible within 60 minutes) alongside ultrasound STOP criteria to rule out contraindications prior to femoro-femoral cannulation.
  • The operational workflow mandates a target interval of ≤15 minutes from the initiation of procedural steps to active extracorporeal blood flow.
  • Standardized checkpoints integrate real-time ultrasound guidance, failed-access algorithms, air-free circuit connections, post-flow stabilization, and expedited transport to a specialized cardiovascular center.
  • No patient-level outcome metrics are reported, with clinical feasibility, safety, survival rates, and neurological outcomes designated for prospective evaluation after launch.

Cite This Study

Sári et al. (2026) studied this question.

synapsesocial.com/papers/6a895ec3ca7ade938187cee5https://doi.org/10.3390/ecm3030027
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