Case report reveals distinct presentation and imaging of bilateral intrathyroid thymic carcinoma in an older male, highlighting diagnostic markers to prevent misclassification.
Background:Intrathyroid thymic carcinoma (ITTC) is a low-grade malignant tumor that arises within the thyroid gland and represents a rare subtype of thyroid neoplasms. It exhibits histological and immunophenotypic features similar to those of thymic carcinoma . The first case was reported by Miyauchi et al. in 1985 . Methods:We present a case of a 60-year-old male patient with multiple bilateral cervical lymph node metastases. Results:The patient underwent an extended radical resection for bilateral thyroid cancer combined with mediastinal lymph node dissection following admission. As of the latest follow-up, 9 months have elapsed since the completion of treatment. Conclusions:This case represents a rare condition that is easily misdiagnosed as primary squamous cell carcinoma, poorly differentiated thyroid carcinoma, anaplastic carcinoma, medullary carcinoma, or other similar malignancies. Herein, we describe its imaging characteristics in detail and aim to facilitate diagnosis and treatment by integrating clinical and imaging findings.
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Zheng et al. (2026) studied this question.
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