What does this research mean for the field?

Surgical excision of wrist ganglion cysts is associated with a lower recurrence rate than aspiration, though this advantage is primarily driven by observational data and is not statistically significant in randomized trials. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To systematically evaluate and compare the recurrence rates of wrist ganglion cysts following treatment with aspiration versus surgical excision.

August 22, 2026Libyan International Medical University JournalOpen Access

Aspiration versus Surgical Excision for Wrist Ganglion Cysts: A Systematic Review and Meta-analysis

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Authors

MGMuhammad Ramadhan Ghifari GFGhossan Faisol FFFaiq Faisol

Discussion

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Overview

Systematic review and meta-analysis reveals lower recurrence rates with surgical excision than aspiration for wrist ganglion cysts, indicating a need for individualized treatment.

Key Points

To systematically evaluate and compare the recurrence rates of wrist ganglion cysts following treatment with aspiration versus surgical excision.
Searched PubMed, Scopus, and ScienceDirect through April 2025 for studies comparing recurrence rates between aspiration and surgical excision in patients with wrist ganglion cysts.
Assessed study quality using Risk of Bias 2.0 and ROBINS-I tools and pooled data using random-effects meta-analysis across 19 studies totaling 1,633 patients.
Surgical excision significantly reduced the overall recurrence rate compared with aspiration (RR: 0.46; 95% CI: 0.30–0.69; I² = 73%; p = 0.0002).
Subgroup analyses showed reduced recurrence with surgery in cohort studies and dorsal ganglia cases, but the difference was not statistically significant in randomized studies (RR: 0.34; 95% CI: 0.11–1.04; p = 0.06).

Cite This Study

Ghifari et al. (2026) studied this question.

synapsesocial.com/papers/6a895eeeca7ade938187d29d https://doi.org/10.1055/s-0046-1827020

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August 22, 2026Libyan International Medical University JournalOpen Access

Aspiration versus Surgical Excision for Wrist Ganglion Cysts: A Systematic Review and Meta-analysis

View Full Paper

Ask AI

Bookmark

Authors

MGMuhammad Ramadhan Ghifari GFGhossan Faisol FFFaiq Faisol

Discussion

Member takes

Overview

Systematic review and meta-analysis reveals lower recurrence rates with surgical excision than aspiration for wrist ganglion cysts, indicating a need for individualized treatment.

Key Points

To systematically evaluate and compare the recurrence rates of wrist ganglion cysts following treatment with aspiration versus surgical excision.
Searched PubMed, Scopus, and ScienceDirect through April 2025 for studies comparing recurrence rates between aspiration and surgical excision in patients with wrist ganglion cysts.
Assessed study quality using Risk of Bias 2.0 and ROBINS-I tools and pooled data using random-effects meta-analysis across 19 studies totaling 1,633 patients.
Surgical excision significantly reduced the overall recurrence rate compared with aspiration (RR: 0.46; 95% CI: 0.30–0.69; I² = 73%; p = 0.0002).
Subgroup analyses showed reduced recurrence with surgery in cohort studies and dorsal ganglia cases, but the difference was not statistically significant in randomized studies (RR: 0.34; 95% CI: 0.11–1.04; p = 0.06).

Cite This Study

Ghifari et al. (2026) studied this question.

synapsesocial.com/papers/6a895eeeca7ade938187d29d https://doi.org/10.1055/s-0046-1827020

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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