What does this research mean for the field?

A novel multi-physics model and closed-loop control method with a 20% dynamic duty cycle can accurately anchor the focal region in high-intensity focused ultrasound and reduce unsuccessful mechanical over-kill by 99.4%. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To elucidate the multiscale interactions between boiling phase transitions and inertial cavitation during high-intensity focused ultrasound to prevent lesion distortion and off-target damage.

August 22, 2026Journal of VibroengineeringOpen Access

Energy transfer through boiling-cavitation interaction in high-intensity focused ultrasound

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To elucidate the multiscale interactions between boiling phase transitions and inertial cavitation during high-intensity focused ultrasound to prevent lesion distortion and off-target damage.
Developed a multiscale multiphysics framework combining a pure enthalpy phase-transition model with an updated Keller-Miksis equation accounting for solid-phase shear elasticity.
Reconstructed two-dimensional acoustic fields to map bubble cloud shielding and simulated a phase-transition surrogate model with transient acoustic pressure gating operators.
Designed a closed-loop control strategy implementing a 20% dynamic duty cycle to optimize thermal relaxation.
Identified a latent heat temperature clamping effect locked at 100±1 °C (latent heat ≈ 2.37×10^9 J/m^3) and bubble wall collapse speeds reaching a Mach number of 1.2.
Showed that bubble cloud shielding drives asymmetric tadpole-shaped lesion distortion in the focal zone.
Achieved focal region temperature stabilization at 78.4 °C and reduced unsuccessful mechanical over-kill by approximately 99.4% using the 20% dynamic duty-cycle method.

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Implication

Computational modeling study demonstrates that dynamic duty-cycle pulsing mitigates cavitation-induced lesion distortion in tissue ablation, highlighting a mechanism to prevent off-target damage.

Cite This Study

DONG et al. (2026) studied this question.

synapsesocial.com/papers/6a895f0dca7ade938187d672 https://doi.org/10.21595/jve.2026.26622

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Implication

Computational modeling study demonstrates that dynamic duty-cycle pulsing mitigates cavitation-induced lesion distortion in tissue ablation, highlighting a mechanism to prevent off-target damage.

Energy transfer through boiling-cavitation interaction in high-intensity focused ultrasound

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Discussion

Implication

Cite This Study

Energy transfer through boiling-cavitation interaction in high-intensity focused ultrasound

Key Points

Discussion

Implication

Cite This Study

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